How do you dose or sequence therapy to overcome radioresistance from oligometastatic disease from RCC?
Do you typically recommend SBRT? What dose? Or do you ever recommend surgery or surgery followed by XRT?
Answer from: Radiation Oncologist at Academic Institution
RAPPORT (NCT02855203) [Siva et al., PMID 34953600] was a phase I/II trial which used a combination of RT and pembrolizumab. RT was given with SBRT (20 Gy/1# prescribed to the 80% isodose line) or conventional radiotherapy (30 Gy/10#) when the treatment volume was in close proximity to a dose-limitin...
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