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How do you evaluate a patient with MGUS and peripheral neuropathy?

Can you explain when would you consider light chain amyloidosis work up with fat pad biopsy?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · University of Chicago
Answered on

When I see a patient with MGUS and peripheral neuropathy, I think about it in stages:

  1. Does the patient have an IgM-monoclonal gammopathy? If so, then I think about DADS-M. An EMG/NCS, anti-MAG antibody, PET scan, and bone marrow biopsy are generally all part of the workup. I try to do MYD88 testing...

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