How do you evaluate patients who have panuveitis without any systemic symptoms?

Although many patients with panuveitis or another anatomic subset of uveitis might have a systemic disease such as sarcoidosis, Behcet's disease, ankylosing spondylitis, or inflammatory bowel disease, often a systemic disease is not diagnosable. A thorough history is the best way to suspect a systemic illness since diseases like Behcet's, ankylosing spondylitis, and inflammatory bowel disease are usually symptomatic. The history should also consider family history (as might suggest Blau syndrome) and travel or exposure history (which might suggest TB, HIV, Lyme disease, or other infectious causes). Assuming that the history has not pointed toward a potential specific cause, a chest x-ray is a good screen for sarcoidosis (a systemic disease ...