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How do you incorporate next gen sequencing results into your management of pediatric patients with B-ALL who have not been transplanted?

With the new COG leukemia studies, it is difficult to interpret these results in the context of their clinical status and conventional MRD
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For a patient with B-ALL, do you act upon positive next gen sequencing when MRD is below the level of clinical detection?

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1 Answer
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Pediatric Hematology/Oncology · M.D. Anderson Cancer Center
Answered on

We enroll in the EndRAD SCT trial which is guided by NGS results.

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