How do you manage a possible autoimmune sialadenitis arising from checkpoint inhibitor therapy?
Patient with primarily oral sicca symptoms, but negative SS-A and SS-B. Mildly positive RF. Lack of improvement with first-line xerostomia treatments.
1 Answer
Mednet MemberInvited Expert
Rheumatology · Ohio State University
Answered on
This is a great question and a common clinical scenario in patients receiving immune checkpoint inhibitors. In my experience, severe sicca symptoms from immunotherapy are often not classic primary Sjögren's syndrome, despite some overlapping features. Rather, this appears to be an acute T-cell-media...
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