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How do you manage a symptomatic primary breast tumor in a patient with metastatic disease?

Do you think it is better to manage symptomatic breast primary disease with radiation or mastectomy in a metastatic patient who has persistent or recurrent breast symptoms while on systemic therapy?
2 Answers
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Radiation Oncology · Beth Israel Deaconess Medical Center
Answered on

It’s much harder to treat patients palliatively than to cure. The art of palliation generally requires weighing the acute and subacute toxicities of alternative treatments much more heavily and chronic toxicities less than we do for potentially curative care. It also requires assessing whether patie...

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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

This is a prospective study showing excellence and durable palliation and favors this ultrahypfractionared 5 fraction approach with sequential or SIB boost

Chatterjee et al., PMID 36868522

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