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How do you manage anemia associated with belzutifan therapy?

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Are you comfortable using erythropoiesis stimulating agents to treat anemia from belzutifan?

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1 Answer
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Medical Oncology · Vanderbilt-Ingram Cancer Center
Answered on

Anemia is a common toxicity with belzutifan. In a recent pooled safety analysis (Choueiri et al., The Oncologist KCRS Meeting 2024), anemia was seen in 84% of patients (any grade; 29% grade 3) with a median time to onset of 29 days. It is an on-target effect resulting from HIF regulation of erythrop...

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