How do you manage anemia in a patient with myelofibrosis and hemochromatosis?

It is a good question. There isn’t much more you can do. There are new targeted therapies for myelofibrosis which are best answered by an MPD specialist. As for the hemochromatosis, you should still check iron parameters, because if deficiency is present it SHOULD be treated, in this case with IV ir...

I agree, a very difficult problem. You can still work down the typical pathway for treating anemia in myelofibrosis, by using epo levels to determine if an ESA can be used. If the epo level is high then consider alternatives like luspatercept (based on a phase 2 study in MF) or danazol.

There is dat...