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How do you manage clozapine related sedation for patients who have treatment resistant Schizophrenia and otherwise had good response to clozapine?

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Mednet Member
Mednet Member
Psychiatry · Maine Medical Center Outpatient Adult Psychiatry

I have colleagues who use modafinil to address the daytime sedation. I've only tried this once, and the patient had intolerable headaches from the lowest dose of modafinil, so I can't say that I've used this successfully.

Strategies I've used with other sedating meds include taking the medication e...

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