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How do you manage erythrocytosis secondary to sotatercept for patients with PAH?

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Mednet Member
Mednet Member
Pulmonology · Temple University Hospital

I have not done that yet, but I have let Hgb drift up to 18-19 and monitor the patient closely. I lower the dose to 0.5 or even 0.3, if Hgb is high at baseline, then start and stay at 0.3 before I increase. I will consider phlebotomy if the above options are not available.

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