How do you manage patients who develop SIADH secondary to an SSRI but have had a strong positive response to that same medication?

Management of SSRI-induced SIADH depends on the severity of hyponatremia and the patient’s psychiatric response to treatment. In mild cases (serum sodium >130), I always continue SSRI with close monitoring and fluid restriction. Moderate to severe hyponatremia, I discontinue SSRI and actively correc...

I had a patient like this, who I had on sertraline 400 mg to get her OCD (comorbid schizophrenia and pervasive developmental delay), who was doing good until she started drinking 6 gallons of water a day. There was a case report that showed switching to Prozac helped. I changed the patient to Prozac...