How do you manage patients with SLE undergoing assisted reproductive therapy with estrogenic effects?

For patients undergoing any form of assisted reproductive technology (ART), it is important to assess their SLE disease activity. If a patient has moderate to severe SLE disease, I recommend delaying ART until we have better control of their disease. Once we plan to move forward with ART, I check antiphospholipid antibodies (if they have not been checked previously) as the presence of these antibodies changes my management.

Type of ART

The type of assisted reproductive technology (ART) is certa...

There are a few key questions to answer here that @Dr. First Last pointed out as there is not a generic answer for all SLE patients:

1. Does the patient want to become pregnant now or freeze eggs/embryos for the future? I assume they are doing IVF from the post, although ART can also include using medication to increase follicle formation, doing IUI, and using a "trigger" shot during an unmedicated cycle.
2. Does the patient have +APLs or >1gm proteinuria or meets criteria for obstetric APS?
3. Have th...