How do you manage prostate cancer in patients that cannot swallow pills?

Are there specific AR Pathway inhibitors that can be crushed and used through feeding tube or would you just avoid ARPIs in such patients?

2 Answers

Mednet MemberInvited Expert

Medical Oncology · VCU Massey Comprehensive Cancer Center

Answered on

The only one suitable for feeding tube administration is apalutamide (must be 8 French or greater feeding tube size).

My oncology pharmacist suggests tablet(s) can be placed in a syringe (whole, not crushed), distilled water then added, shaken vigorously to disperse contents, administered through...

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Mednet Member

Medical Oncology · Memorial Sloan Kettering

Answered on

I would either use apalutamide or avoid ARPIs entirely

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