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How do you manage radiation plexopathy?

How does this strategy change depending on the acuity or chronicity of the symptoms?
3 Answers
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Radiation Oncology · Beth Israel Deaconess Medical Center
Answered on

This is a frustrating problem. I agree that there are no proven treatments for radiation plexopathy. However, chronic radiation injuries appear due at least in part to an ongoing inflammatory process. Interrupting this process with pentoxifylline and Vitamin E has been successful in reversing fibros...

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Neurology · University of Minnesota
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Radiation-induced brachial or lumbosacral plexopathy is typically not an acute disease; it slowly progresses over months to years. Unfortunately, there is nothing beyond symptomatic management (of pain, cramps, or myokymia) that has been proven to work. I do not use steroids or anticoagulants. Physi...

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Radiation Oncology · Locum Tenens
Answered on

Frustrating problem, we need better treatments for this and other late radiation fibrotic events.

There is anecdotal and animal evidence for the leukotriene inhibitor, montelukast preventing or ameliorating fibrosis in a variety of systems. As you know, this drug is used for the treatment of asthma a...

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