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How do you manage radiotherapy for a glioblastoma when there is a delay in starting systemic therapy?

Temodar can sometimes take 2-3 weeks to arrive after prior approval. Would you start radiotherapy without Temodar or wait for it to arrive and begin concurrently?
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How do you manage RT for a glioblastoma when there is a delay in systemic therapy?

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1 Answer
Mednet Member
Mednet Member
Radiation Oncology · Cancer Care Centers of Brevard
Answered on

It depends on whether we are discussing a post op vs unresectable patient.

It is okay to delay in post op imo up to 4-6 weeks out after a GTR. I would not start within 2 weeks after biopsy, regardless of temodar authorization in an unresectable patient.

Blumenthal et al., PMID 19114694

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