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How do you manage Raynaud's symptoms that develop in patient on CGRP inhibitors?

Do you just switch to alternative therapy, or use medications or supplements to try and improve Raynaud's symptoms?
1 Answer
Mednet MemberInvited Expert
Neurology · Greater Boston Headache Center at Boston Advanced Medicine
Answered on

Research and practice combined, I have worked with the CGRP-receptor antagonists or gepants and CGRP-antibodies for over 20 years. I have not seen or heard of Raynaud's symptoms as a side effect of those medications, which, across the board, are very well tolerated. Hence, I would like to learn more about it, maybe from the person asking the question. My treatment recommendation for Raynaud's symptoms in general is a calcium antagonist, which may additionally help a little to prevent the migraine headaches. Vasodilators, in my opinion, are better avoided in migraineurs.

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