How do you manage recurrent inoperable chest wall pleomorphic liposarcoma with prior radiation therapy?

Prior treatment: GTR in 2020, adjuvant radiation 63Gy

Patient factors: Medically inoperable and not fit for chemotherapy

The recurrence is within the prior radiation field

Answer from: Radiation Oncologist at Academic Institution

Palliatively. But review the case and see if anything could be done differently next time. Local control of STS with proper surgery and radiation should be excellent. Perhaps there was a positive surgical margin that should have been re-resected, perhaps postop RT wasn't properly designed, etc. With...

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Radiation Oncologist at BASS Cancer Center
Thank you! Unfortunately, there have been multiple...

Answer from: Radiation Oncologist at Community Practice

Several things are notable about this case Medically inoperable 2 years after GTR. The patient must have had some issues at the time of original surgery. How much time between surg and the start of radiation? Any CTX at original TX. Location of tumor, OAR doses, radiation technique. ...

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