How do you manage significant fatigue caused by androgen deprivation therapy in prostate cancer patients?

This is a great question and one that I think comes up regularly in the clinic. The fatigue often is due to the hypogonadal state, lack of muscle mass and subsequent loss of muscle power that may reduce stamina.

I generally recommend a regular activity or exercise program. As in many other patient p...

I agree to an extent with the above commentary. #1. All studies relating to fatigue have to ensure that specific factors are excluded from analysis. For example, I would also exclude anemia of androgen deprivation (AAD) as a cause. A small percentage of men will decrease their HCT to < 30% on androg...