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Topics:
Genitourinary Cancers
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Medical Oncology
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Renal Cell Carcinoma
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Nephrology
How do you mange stage IV RCC with high tumor burden responding to salvage IO + Cabozantinib but with significant drug associated rise in serum creatinine?
Related Questions
Would you offer adjuvant immunotherapy in a patient with high risk RCC with new/worsening post-op renal dysfunction and CrCl<30?
Would the occurrence of obvious tumor rupture/spillage intraoperatively impact your decision for adjuvant systemic therapy after resection of either clear cell RCC or papillary RCC?
How would you approach the use of bevacizumab in metastatic FH-deficient RCC/HLRCC that is c/b extensive IVC tumor thrombus and DVT/PE?
When, if ever, would you re-challenge with immunotherapy for patients with metastatic RCC?
What is your approach to surveillance in patients with no evidence of disease after treatment of oligometastatic renal cell carcinoma?
How would you approach adjuvant systemic therapy for an isolated, oligometastatic CNS recurrence of RCC that was treated with SBRT?
How would you treat a patient with metastatic RCC with high grade neuroendocrine and sarcomatoid features after progression on IO + TKI?
In a patient with metastatic RCC who discontinued nivolumab after a prolonged response to ipilimumab/nivolumab, would you consider re-starting nivolumab at disease progression?
How do you manage patients blood pressures while on anti-angiogenic TKIs?
What is your preferred approach to low volume unresectable/metastatic favorable risk RCC?
