How do you mitigate the risk of hearing loss for patients requiring cisplatin?

I have seen some centers do baseline audiometry testing for all patients to at least give a baseline if the patient then complains of tinnitus or other hearing changes during treatment. I'm not sure how much this helps without also doing surveillance during treatment and it hasn't become my standard practice.

I think your suggestion of chemoprevention would need to be studied in an RCT with adults before I'd consider it.