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How do you monitor for cardiac toxicity in patients taking osimertinib?

Do you routinely check EKGs or echocardiograms? Or do you decide only if the patient is at risk for QTc prolongation or other symptoms?
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How do you monitor for cardiac toxicity in patients taking osimertinib?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · University of Colorado Anschutz Medical Center
Answered on
There are multiple studies that have explored the issue of cardiotoxicity from osimertinib. A large single-center retrospective observational cohort series from Taiwan, (n=401) compared a matched cohort of patients treated with osimertinib (n=253) to those treated with other EGFR TKIs (n=195) and fo...

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