How do you now approach treatment sequencing in MM in light of the DETERMINATION trial data?

There are two questions that come to mind re: DETERMINATION with respect to sequencing.

1) To do early transplant or not?

2) To do indefinite lenalidomide maintenance?

My views on question #1 are evolving, but here is how I have unpacked it and stated elsewhere on theMednet.

REASONS TO DO TRANSPLANT:

...

The DETERMINATION trial is the U.S. half of the IFM-DFCI 2009 trial - the results from the French patients with fixed duration of Revlimid maintenance have already been published. Since I already continue maintenance until toxicity or resistance, DETERMINATION didn't change my practice.

On the other...