Well differentiated NETs span the Ki67 proliferation spectrum of 0% to well above 50% and have a very variable, and at times unpredictable, history. Grade 3 well differentiated NETs are increasingly recognized. A general rule, but not perfect, is that higher Ki67 predicts more aggressive tumors. Tum...

The specific means by which I perform surveillance on metastatic well differentiated NET patients is dictated by disease biology (grade) and the specific treatment they are undergoing. I don't use chromogranin A given the number of false positives, nor do I use gallium dotatate PET scans. Typically ...