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How do you recommend differentiating between localized cutaneous melanoma of the perianal skin versus mucosal melanoma of anal canal?

This question arises from a case of a patient with multifocal nodular melanoma with circumferential involvement of the perianal region.
1 Answer
Mednet Member
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Medical Oncology · University of Colorado
Answered on

Although perianal melanomas arise within squamous epithelium, I think it is better to characterize these as mucosal melanomas. I think of it as being similar to melanomas that arise within the cutaneous surface (i.e. squamous epithelium) of the vulva but are still considered to be mucosal melanomas....

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