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How do you recommend mitigating the risks of using beta blocker and clonidine therapy in combination for management of hypertension?
Answer from: at Community Practice
Beta blockers vary in lipophilicity, which affects blood-brain barrier permeability. Propranolol and metoprolol readily cross the blood-brain barrier, while other beta-blockers like nebivolol do not. The CNS side effects of fatigue, depression, and insomnia are more likely to worsen if using a lipop...
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