How do you reconcile the difference with regard to adjuvant treatment recommendations when a breast biopsy reveals >10% ER+ but a subsequent lumpectomy of the same lesion is ER-negative?

Topics: Breast Cancer • Medical Oncology

Answer from: Medical Oncologist at Academic Institution

Situations such as this typically involve review with pathology, including a second opinion review, to settle on one of two basic camps of possible explanations: 1. Heterogenous cancer or even possibly multiple primaries with differing receptors. Although not common, some cancers are heterogeneous ...

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Medical Oncologist at HOCI
Would u still use Antiestrogens?

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