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How do you schedule IV/PO Dexamethasone if giving immunotherapy concurrently with chemotherapy in patients with NSCLC?

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Do you adjust steroid premeds for chemotherapy when used in a regimen including immunotherapy?

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1 Answer
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Medical Oncology · The Ohio State University School of Medicine
Answered on

We follow the methods listed in the clinical trial publications. For instance, KEYNOTE-189 followed standard steroid pre-medications for pemetrexed, and KEYNOTE-407 did the same for paclitaxel. Since the monoclonal antibodies tend to have long half lives and steroid premeds are given for such a shor...

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