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How do you sequence ADT relative to the start of RT?

Given the publication by Malone, et al (JCO, 2019), how do you sequence ADT relative to the start of RT? https://ascopubs.org/doi/full/10.1200/JCO.19.01904
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When do you start ADT relative to the start of RT?

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2 Answers
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Radiation Oncology · Case Western Reserve University/ University Hospitals Seidman Cancer Center
Answered on

Happy New Year to the MedNet! This is a great question that should remind us to question everything.

This is an important question that the prostate community I have felt since I was in training has over simplified for decades.

First: Our current nomenclature has problems. Most residents and facult...

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Radiation Oncology · UC San Diego
Answered on

Yes, this was an interesting study by Malone et al., which I enjoyed reading. Given the lack of significant advantage to either approach on the study, we continue to typically give 2 months of neoadjuvant ADT.

As opposed to the 3DCRT approach on the study, we use VMAT with fairly tight margins (3-4...

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