How do you set practical referral and discharge criteria for a MASLD multidisciplinary clinic to capture high-risk phenotypes without being overwhelmed?

As former Director of the Penn State Health Fatty Liver Program, we structured our multidisciplinary MASLD clinic around risk stratification rather than diagnosis, with the explicit goal of capturing patients at genuine risk of progression while preserving clinic capacity.

We relied on a two‑step triage model that kept low-risk MASLD in primary care and escalated only those patients where coordinated specialty care could realistically change outcomes. FIB-4 was our front‑end screening tool, with...