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Topics:
Medical Oncology • Rheumatology • Myeloproliferative Neoplasms • Hematology • Allergy & Immunology
How do you think about using Ropeginterferon Alfa 2B for polycythemia vera in patients with active autoimmune disease?
Would you consider this an absolute contraindication? What if the autoimmune disease was stable and not active?
Answer from: at Community Practice
Great question. In general, I avoid interferons in patients who have an autoimmune disease. In the PROUD-PV/CONTI-PV study, a medical history of autoimmune disease was an exclusion criterion. There have been reported cases of interferon-induced autoimmune disease, most commonly autoimmune thyroiditi...
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