How do you transition patients between different long-acting injectable antipsychotics?

When it is time for the next dose of LAI #1, administer LAI #2 instead. Use an equivalent dose to produce equivalent dopamine receptor activity. To determine the equivalent dose, consider the maximum recommended dose of #1 to be equivalent to the maximum recommended dose of #2. With all the sophisti...

I only had to do this twice and generally followed the simple rule of minimal dosage to minimal dosage, medium to medium, and of course, maximum to maximum. People tolerated the switch flawlessly and without any trouble.

NOT scientific at all. Intuitive. Given the lack of guidance, it still worked.