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How do you treat a primary pineal neoplasm of intermediate differentiation?

Would extent of surgical resection matter? Do these patients need CSI (like Pineoblastoma), just local radiation, or something in-between (say whole ventircular or whole brain + boost)?
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How would you treat a resected primary pineal neoplasm of intermediate differentiation?

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2 Answers
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Radiation Oncology · Columbia University Irving Medical Center
Answered on

Pineal parenchymal tumors of intermediate differentiation (PPTID) represent a rare type of intracranial tumor that behaves somewhere between pineocytomas and pineoblastomas. Given the rarity of PPTID, data is limited to retrospective studies with no clear consensus on adjuvant therapy. In general, a...

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Radiation Oncology · Icahn School of Medicine at Mount Sinai
Answered on · Updated on

I completely agree with Dr. @Dr. First Last in that a multi-disciplinary discussion is critical when it comes to managing PPTID and given lack of prospective data there is no consensus (and probably there will never be given the rarity of this disease).

Incidentally, in the past 3 months, our clinic ...

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