How do you treat anal adenocarcinoma?

Topics: Radiation Oncology • Gastrointestinal Cancers

Is the approach chemoradiotherapy (Mitomycin-5FU) as for squamous carcinoma with surgery only for salvage or do you always perform surgery after neo-adjuvant chemoradiotherapy? In that case do you limit the dose to 50 Gy?

Answer from: Radiation Oncologist at Academic Institution

First of all you have to define what you are dealing with. Adenocarcinoma of the anal canal is a rare condition arising from anal glandular tissue. There is no IHC marker or definitive histologic finding that can differentiate it from rectal cancer with extension into the anal canal. The suggestive...

Comments

Radiation Oncologist at Cancer Care Center
Would you treat the inguinal regions prophylactica...

Radiation Oncologist at Memorial Sloan-Kettering Cancer Center
It is important to recognize that ACA of the anal ...

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