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How do you treat anal adenocarcinoma?

Is the approach chemoradiotherapy (Mitomycin-5FU) as for squamous carcinoma with surgery only for salvage or do you always perform surgery after neo-adjuvant chemoradiotherapy? In that case do you limit the dose to 50 Gy?
1 Answer
Mednet Member
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Radiation Oncology · Memorial Sloan-Kettering Cancer Center
Answered on

First of all you have to define what you are dealing with. Adenocarcinoma of the anal canal is a rare condition arising from anal glandular tissue. There is no IHC marker or definitive histologic finding that can differentiate it from rectal cancer with extension into the anal canal. The suggestive ...

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