How do you treat fatigue symptoms in myasthenia gravis?

Fatigue is one of the most common symptoms in patients with MG. Pyridostigmine can give patients symptomatic relief. In addition, we look for other causes, including sleep disorders (insomnia from steroid use, obstructive sleep apnea), comorbidities (heart disease, hypothyroidism, adrenal insufficie...

Importantly, especially in myasthenia gravis, but also in other neuromuscular disorders, we try to differentiate between peripheral fatigue (i.e., fatigability of the muscles due to reduction in the safety factor at the neuromuscular junction leading to worsening muscular function and fatigability a...