How do you treat metastatic mesenchymal chondrosarcoma?

Mesenchymal chondrosarcoma is a rare aggressive variant of chondrosarcoma that is treated like a Ewing sarcoma. As with all chemotherapy, the patient's performance status should be acceptable to proceed with the chemotherapy which can be difficult to tolerate. If confirmed to be mesenchymal chondrosarcoma by pathology review at an experienced sarcoma center, then this would be considered a high grade tumor.