How do you treat multisystem sarcoidosis refractory to methotrexate, humira, and remicade?

There are many layers to this question because there are many possible explanations for treatment failure. The first issue to consider is whether the specific features of sarcoidosis being treated are best addressed through an immunosuppressive approach. Some manifestations of sarcoidosis may be ind...

Given the limited number of randomized controlled trials to help guide treatment decisions in sarcoidosis, we often turn to more limited studies or anecdotal data. Currently, we view treatment as first-line (corticosteroids), second-line (oral immunosuppressants such as methotrexate, azathioprine, l...