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How do you treat patients with stroke thought to be secondary to Lambl excrescence?

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What is your preferred antithrombotic regiment for prevention of stroke secondary to Lambl's excrescences?

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2 Answers
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Neurology · University of Virginia, School of Medicine
Answered on

Pathophysiologically, these occur through sheer stress to the valvular endocardium causing small areas to be denuded followed by fibrin deposition and microthrombi formation on the endocardial injury, which can embolize. Histopathologically, they have similarities to fibroelastomas (which are larger...

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Mednet Member
Mednet MemberInvited Expert
Neurology · Vanderbilt University Medical Center
Answered on

The definitive treatment is surgical removal. If that is not possible, then I would try anticoagulation, but without much evidence of efficacy.

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