How do you treat stage I head of pancreas adenocarcinoma in an older patient who is not a candidate for chemotherapy or surgery?

The question of how to manage an elderly patient who is not a candidate for chemotherapy or surgery is a really important one. I would argue that this question is not unique to an elderly patient but should be asked for ANY patient who cannot receive systemic therapy. We are fortunately living in a ...

The MDACC data are with pre-operative treatment in surgical candidates. Many are now giving ablative doses with median OS results >2 years in these patients that are similar to surgery. Our recent results (Reyngold et al., PMID 33704353, Jolissaint et al., PMID 34269717) show this in much worse pati...