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How do you treat TBI-associated aggression?

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In a 30 year old male with new onset TBI associated aggression and no prior past psychiatric history what would be your first medication of choice?

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2 Answers
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Psychiatry · South Broward Hospital District
Answered on

Propranolol has the best evidence, but you can also consider Depakote (since there is an increased risk of seizure as well) or an atypical antipsychotic.

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Mednet Member
Mednet Member
Psychiatry · Thapar Renu K Office
Answered on

Aggression with TBI is often associated with impulsivity and seizure disorder.

Depakote offers a safe choice for the impulsive anger and seizure disorders.

Propanolol is helpful to cut down the sympathetic tone, and thus calming patients.

SGAs are good for PRN use and add-on if the full dose of Depa...

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