How do you treat the seminal vesicles when using moderate hypofractionation for prostate cancer?

The question refers to moderate hypofractionation and I will begin by defining moderate hypofractionation. In my book moderate hypofractionation involves daily fractions of 2.4-4 Gy/day as opposed to 1.8-2 Gy/day which remains the norm in the United States. There are several prospective reports of moderate hypofractionation but, in the interest of concision, I will summarize how the seminal vesicles were treated in the three large non-inferiority (NI) trials.

NRG Oncology 0415 included only low r...