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How do you use daratumumab in the treatment of systemic AL amyloidosis?

What regimens would you consider combining it with? Any specific combinations to avoid or special considerations?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · University of Nebraska Medical Center
Answered on

I now routinely incorporate daratumumab into the frontline treatment for AL amyloidosis as well as in the relapsed/refractory setting. The data supporting frontline use comes from the phase III ANDROMEDA study which randomized patients to Dara-CyBorD to CyBorD (cyclophosphamide, bortezomib, dexameth...

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