How do you utilize PRAME for melanocytic biopsies?
Do you use it for excisions to determine if margins are clear?
Do you use it for all melanocytic biopsies?
How do you balance using PRAME with the fact that some studies show that PRAME does not stain some melanomas?
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How do you utilize PRAME for melanocytic biopsies?
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Dermatology · Eastern Virginia Medical School
Answered on
PRAME is useful as one piece of information to help me decide if I have enough criteria for melanoma in situ. Like most IHC stains it is just a piece of the puzzle to me. In my experience, positivity of MIS is about 7-8/10, so I do not require PRAME positive to diagnose MIS. But positive PRAME helps...
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