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How do you wean patients off cenobamate in the EMU and how long can these patients be off of it before having to restart the two month uptitration?

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Mednet Member
Mednet Member
Neurology · Massachusetts General Hospital

Our practice includes titration by 50-100mg/day. We then titrate back up 50-100mg/day. We also take into consideration of any history of status or refractory breakthrough seizures. Also, most patients who are on cenobamate are on multiple other ASM so we titrate those first if possible and titrating...

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