How do you weigh upfront nodal burden when deciding to omit PMRT in a patient with cN1, ypN0 disease after neoadjuvant chemo, mastectomy and ALND?

For example, if the patient had several abnormal nodes radiographically vs 1-2.

Answer from: Radiation Oncologist at Community Practice

Pre-chemo imaging if it shows 4 or more abnormal nodes (N2) then would offer RNI irrespective of response.