How do you work up and manage an ESKD patient with controlled blood pressure who complains of recurrent headaches while on hemodialysis?

First, I would consider obtaining a head CT to exclude intracranial hemorrhage, given the increased bleeding risk associated with heparin anticoagulation and uremic platelet dysfunction.

In a patient who is clinically stable, has well-controlled blood pressure, and experiences headaches clearly asso...

Migraines are actually not uncommon in dialysis patients, and at times, dialysis initiates them. If Tylenol is not enough, I would try Imitrex right before dialysis.