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How does a mildly elevated CBG (cortisol binding globulin) level affect the interpretation of the 1mg overnight dexamethasone suppression test results?

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Mednet Member
Mednet Member
Endocrinology · Johns Hopkins Department Of Endocrinology Diabetes And Metabolism

We usually do not measure CBG level during the 1-mg DST. If a woman is on oral estrogen, one may wait for the total cortisol level; if abnormal, repeat the test with free cortisol measurement or measure free cortisol proactively to avoid delays in test interpretation. A nice paper from the Mayo Clin...

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