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How does a patient who is PNPLA-3 positive (heterozygote or homozygote) impact how you formulate their therapeutic plan?
Answer from: at Community Practice
At this time, the PNPLA3 positive status (heterozygote or homozygote) does not impact my formulation of a therapeutic plan, as my decisions to treat (and how to treat) are based on underlying MASLD disease activity and severity. My treatment decisions are tailored to patients' underlying risk factor...
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Answer from: at Academic Institution
In my current practice, I am not impacted by this status. However, in patients who are homozygous, I would counsel the patient on the potential for more pronounced disease acceleration. I do not routinely check this in my practice either.