How does clinical intramammary lymph node involvement in HER2+ breast cancer affect your neoadjuvant chemotherapy choice?
Would you prefer TCHP over TCH? Would you consider adding an anthracycline?
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What neoadjuvant chemotherapy do you use for HER2+ breast cancer with intramammary lymph node involvement?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · University of Texas MD Anderson Cancer Center
Answered on
The AJCC 8th edition classifies an intramammary node as an axillary node (1). Intramammary nodes are associated with axillary involvement although their independent contribution to recurrence risk remains controversial. Accordingly, I would recommend neoadjuvant TCHP in this case (I drop carboplatin...
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