How does HBV/HDV coinfection after liver transplant change your functional cure targets (HBsAg loss/anti-HBs) and your tolerance for residual HBV activity markers (e.g., HBcrAg or pgRNA) compared with HBV monoinfection?

HBV/HDV infection after transplant is no different from pre-transplant. Functional cure is still the goal for HBV, although HBsAg clearance may not clear the Delta virus. There is, however, a treatment for Delta now approved in the US. Core antigen and pgRNA are not available commercially and do not...