How does SUPREMO alter your recommendations for PMRT?  

The recent SUPREMO trial provides data that might alter my prior posts on the topic of PMRT. The SUPREMO trial demonstrates that chest wall RT alone, in a relatively favorable subgroup of patients, is not helpful.Regarding T3N0, I previously wrote on MedNet: "When treating PMRT in the pT3N0 setting,...

There has been a very long debate as to which, if any, patients having upfront mastectomy and axillary surgery who are found to have 1-3 positive axillary nodes (pN1) benefit from post-mastectomy radiation therapy (PMRT). I gave my thoughts in this forum on the implications of the "SUPREMO" trial fo...